Pharma Times, India's first magazine in pharma World. Drug resistance is turning into one of the world's most pressing public health problems of today with some of the infectious diseases becoming untreatable with the existing drugs. Resistance is being experienced more in the case of antibiotics used as the doctors tend to prescribe that class of drugs as an easy option even for a minor infection. And there has been no control over the prescriptions written by doctors because it is a technical work and the authorities left that decision totally to their judgment. Almost 50 percent of antibiotic prescriptions in the developing world and in some developed countries are not actually needed for treating diseases. Antibiotics need to be prescribed in optimal doses, regimens, and should be stopped when the infection is treated. It is important that the use of last-line antibiotics should be restricted to serious infections and only when simpler therapeutic agents turn ineffective. Now, with the emergence of microorganisms which developed antibiotic resistance, humanity is once again facing a major threat of many incurable infectious diseases. Drug-resistant infections are difficult to treat and have resulted in an increase in medical costs and mortality in recent years.